Rabbit Anti-Phospho-Syk (Tyr525 + Tyr526) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-Syk (Tyr525 + Tyr526)
IR:Immunogen Range:EN(p-Y)(p-Y)KA
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6850
Swiss Prot:P43405
Source:KLH conjugated Synthesised phosphopeptide derived from human Syk around the phosphorylation site of Tyr525/526:EN(p-Y)(p-Y)KA
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Syk (72 kDa) is a non receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. Alternate Names: p72syk; Spleen tyrosine kinase; Tyrosine protein kinase SYK.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Rabbit
Guinea Pig
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： Phospho-Syk (Tyr525 ;Syk (phospho Y525) ;p-Syk (phospho Y525);Syk (Phospho Tyr525 ;p72syk Spleen tyros;Syk; Tyrosine protein ki;KSYK_HUMAN;
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