中文名:氰乙酸
英文名:Cyanoacetic acid
应用:Cyanoacetic acid can be used as a reagent:
· Along with acetic anhydride for cyanoacetylation of various pyrroles, indoles, and aniline derivatives. It can also be used in other reactions such as cyclizations, syntheses of coumarins and other heterocycles.
· To prepare of key intermediate via Knoevenagel condensation in the total synthesis of 5-acetamido-substituted melatonin derivatives as MT3 receptor ligands.
· In the synthesis of aminopyrrolinone derivatives by reacting Ugi adducts of cyanoacetic acid and aromatic aldehydes
纯度:≥98%
货号:C105698
Cas号:372-09-8
存储温度:充氩
运输条件:常规运输
产品介绍:
溶于水、乙醇、乙醚。微溶于乙酸、苯和氯仿,具有溶解性,水中溶解度:1000 g/L (20°C)。
Cyanoacetic acid can be used as a reagent:
· Along with acetic anhydride for cyanoacetylation of various pyrroles, indoles, and aniline derivatives. It can also be used in other reactions such as cyclizations, syntheses of coumarins and other heterocycles.
· To prepare of key intermediate via Knoevenagel condensation in the total synthesis of 5-acetamido-substituted melatonin derivatives as MT3 receptor ligands.
· In the synthesis of aminopyrrolinone derivatives by reacting Ugi adducts of cyanoacetic acid and aromatic aldehydes
应用:
氰基乙酸可用作以下反应的试剂:
与乙酸酐一起用于各种吡咯、吲哚和苯胺衍生物的氰基乙酰化(cyanoacetylation)。它也可用于环化、香豆素和其他杂环的合成等其他反应中
。通过Knoevenagel缩合反应制备可作为MT3受体配体的5-乙酰氨基取代褪黑素衍生物的全合成过程的关键中间体。
通过Ugi加成物与氰基乙酸和芳香醛反应合成氨基吡咯啉酮(aminopyrrolinone )衍生物。
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关键字: 氰基醋酸 ; 氰基乙酸;alpha cyanoacetic acid ; cyanoethanoic acid
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