aladdin 阿拉丁 A102398 艾菲地可宁 38966-21-1 98%

中文名：艾菲地可宁

英文名：Aphidicolin

应用：A novel tetracyclic diterpene antibiotic and also a DNA synthesis inhibitor in eukaryotes

纯度：≥98%

货号：A102398

Cas号：38966-21-1

存储温度：2-8°C储存

运输条件：低温运输

产品介绍：

Aphidicolin is a tetracyclic diterpene antibiotic and DNA synthesis inhibitor isolated from Cephalosporium aphidicola. Aphidicolin is reported to specifically inhibit DNA polymerase α and δ via binding to the enzyme, in eukaryotic cells such as the HeLa cell line, without affecting other DNA polymerases. This compound blocks the cell cycle at early S phase and has been reported to be useful for synchronizing cell cycles in cultured eukaryotic cells. This compound is also noted to induce apoptosis in HeLa S3 cells after 18-24 hours of the cell cycle.A novel tetracyclic diterpene antibiotic and also a DNA synthesis inhibitor in eukaryotes

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