中文名:Stauprimide,抑制剂
英文名:Stauprimide
纯度:≥99%
货号:S139814
Cas号:154589-96-5
存储温度:-20°C储存
运输条件:超低温运输
产品介绍:
Stauprimide is an indolocarbazole semi-synthetic small molecule shown to significantly increase the efficiency of directed embryonic stem cell differentiation. Stauprimide inhibits the nuclear localization of NME2, blocking and downregulating c-Myc expression. The expression of c-Myc is crucial for embryonic stem cell self-renewal, and intervention by Stauprimide allows for more efficient lineage-specific differentiation. NME2 is also indicated to be upregulated in certain cancers, indicating further application for the blocking action of StauprimideAn indolocarbazole promoter of embryonic stem cell differentiation.
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关键字: Q7604751 ; [9S-(9alpha,10beta,11beta,13alpha)]-N-(2,3,10,11,12,1 3-Hexahydro-10-methoxy-9-methyl-1,3-dioxo-9,13-epo xy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j] [1,7]benzodiazonin-11-yl)-N-methylbenzamide ; HY-N6747 ; N-((9S,10R,11R,13R)-2,3,10,1
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