中文名:IcilinAG-3-5,TRPM8激动剂
英文名:Icilin,AG-3-5
纯度:Moligand™,≥96%
货号:I303569
Cas号:36945-98-9
存储温度:-20°C储存
运输条件:超低温运输
产品介绍:
General description:
Icilin is a synthetic cooling agent and modulates human transient receptor potential cation channel (TRPA1). Icilin inhibits transient receptor potential cation channel subfamily M member 8 (TRPM8) and modulates calcium release. Icilin also suppresses transient receptor potential vanilloid subtype 3 (TRPV3).
application:Icilin has been used as cooling agent in anterior ventromedial preoptic area (VMPO) neurons.
Biochemical/Physiological Effects:
Icilin is a potent agonist at the CMR1 cold- and menthol-sensitive receptor.
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