中文名:(±)-吴茱萸碱
英文名:(±)-Evodiamine
应用:An antiangiogenic and antiinflammatory agonist of TRPV1.
纯度:≥98%
货号:E140884
Cas号:518-18-3
存储温度:2-8°C储存
运输条件:低温运输
产品介绍:
Evodiamine is a quinozole alkaloid isolated from Evodia rutaecarpa, described as an agonist of the VR1 (vanilloid receptor subtype 1, TRPV1) with affinity (Ki = 5.95 microM) comparable to that of the prototypical VR1 chemical activator Capsaicin .Evodiamine induction of 45Ca2+ uptake was competitively antagonized by the Capsaicin antagonist Capsazepine .Evodiamine is described to inhibit prostaglandin E2 synthesis, cyclooxygenase-2 induction and NF-κB activation, producing antiinflammatory effects.An antiangiogenic and antiinflammatory agonist of TRPV1.
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