中文名:PF 6274484,共价EGFR激酶抑制剂
英文名:PF 6274484
纯度:≥98%(HPLC)
货号:P288199
Cas号:1035638-91-5
存储温度:-20°C储存
运输条件:超低温运输
产品介绍:
PF 6274484 is a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM. PF 6274484 inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and 6.6 nM, respectively.
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