中文名:5-甲氧基-L-色氨酸
英文名:5-Methoxy-L-tryptophan
纯度:≥97%
货号:M353041
Cas号:25197-96-0
存储温度:-20°C储存
运输条件:超低温运输
产品介绍:
General description:
5-Methoxy-L-tryptophan is a L-tryptophan metabolite that exhibits anti-inflammatory and tumor-suppressing activities. 5-Methoxy-L-tryptophan is synthesized by tryptophan hydroxylase (TPH) and hydroxyindole O-methyltransferase (HIOMT). Recent study indicates 5-methoxytryptophan as a biomarker of progression of chronic kidney disease (CKD). Its levels decrease during disease and treatment with 5-methoxytryptophan ameliorates kidney fibrosis n mice model of CKD. 5-Methoxytryptophan appears to inhibit I?B/NF-?B signaling and enhaces Keap1/Nrf2 signaling in mice model of unilateral ureteral obstruction. Literature often uses the name 5-Methoxytryptophan instead L-5-Methoxytryptophan.
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