aladdin 阿拉丁 L412863 龙血素B 119425-90-0 98%

中文名：龙血素B

英文名：Loureirin B

纯度：≥98%

货号：L412863

Cas号：119425-90-0

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

Loureirin B Loureirin B (LB, LrB), a flavonoid extracted from Dracaena cochinchinensis, is an inhibitor of PAI-1 with IC50 of 26.10 μM. Loureirin B downregulates p-ERK and p-JNK in TGF-β1-stimulated fibroblasts. Loureirin B promotes insulin secretion mainly through increasing Pdx-1, MafA, intracellular ATP level, inhibiting the K ATP current, influx of Ca 2+ to the intracellular.

Targets

p-ERK ; p-JNK ; Calcium Channel ; Potassium Channel ; PAI-1 (Cell-free assay) ; 26.10 μM

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