aladdin 阿拉丁 B413030 BMS-986020 1257213-50-5 99%

中文名：BMS-986020

英文名：BMS-986020

纯度：Moligand™，≥99%

货号：B413030

Cas号：1257213-50-5

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

BMS-986020 BMS-986020 (AM152, AP-3152 free acid) is a potent and selective antagonist of lysophosphatidic acid receptor 1 (LPA1) . BMS-986020 inhibits bile acid and phospholipid transporters with IC50 of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF).

Targets

LPA1 ; BSEP (Cell-free assay); MRP4 (Cell-free assay); MDR3 (Cell-free assay) ; 4.8 μM; 6.2 μM; 7.5 μM

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