中文名:Bosutinib (SKI-606)
英文名:Bosutinib (SKI-606)
纯度:Moligand™,10mM in DMSO
货号:B407917
Cas号:380843-75-4
存储温度:-80℃储存
运输条件:特低温运输
产品介绍:
Bosutinib (SKI-606) is a potent c-Abl, Bcr-Abl, and Src-Abl kinase inhibitor, shown to effectively interfere with the progress of chronic myelogenous leukemia (CML). In a competitive study with Imatinib, Bosutinib was shown to inhibit Bcr-Abl kinase activity in CD34+ CML cells more potently than Imatinib. Activity of Src-Abl has been implicated in the development of other non-CML malignancies, and Bosutinib has demonstrated in studies to suppress breast cancer growth and migration.A c-Abl, Src-Abl, and Bcr-Abl inhibitor
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