aladdin 阿拉丁 P421721 Pitavastatin Calcium 147526-32-7 10mM in DMSO

中文名：Pitavastatin Calcium

英文名：Pitavastatin Calcium

中文别名：匹伐他汀钙

英文别名：Pitavastatin calcium|147526-32-7|Pitavastatin hemicalcium|Livalo|Itavastatin calcium|NK-104|Flovas|Pitavastatin calcium salt|UNII-IYD54XEG3W|IYD54XEG3W|NK 104 (acid)|Nisvastatin|CCRIS 8652|Calcium (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl

纯度：10mM in DMSO

货号：P421721

包装：1ml

Cas号：147526-32-7

存储温度：-80℃储存

产品介绍：

Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.

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