
Integrin alpha V beta 6产品信息
英文名称:Integrin alpha-V/beta-6
中文名称:整合素α-V/β-6复合体
靶点别称:Integrin alpha V beta 6,ITGAV&ITGB6
物种:Human / Mouse / Cynomolgus / Rat
属性:Protein / Cell
标记:Biotin-labeled / Unconjugated
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.


Integrin alpha V beta 6分子背景
整合素αVβ6是β6与αV结合的异二聚体。整合素αVα6是纤维连接蛋白和细胞触觉素的受体。它识别其配体中的序列R-G-D。整合素α-Vβ-6通过网格蛋白介导的内吞作用内化,促进癌细胞侵袭。此外,整合素α-Vβ-6作为柯萨奇病毒A9和柯萨奇病毒B1以及单纯疱疹病毒-1/HHV-1的受体。此外,它结合TGF-β潜伏相关肽(LAP),并从大的潜伏复合物中激活TGF-β1或TGF-β3。这种激活需要与LTBP-1和纤连蛋白相互作用,并通过PAR-1增强。
Integrin alpha V beta 6用户评价

关键字: 整合素αvβ6;αvβ6整合素;integrin αvβ6;αvβ6;Integrin alpha V bet;
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