aladdin 阿拉丁 R412671 瑞格列净乙酸酯 442201-24-3 98%

中文名：瑞格列净乙酸酯

英文名：Remogliflozin etabonate (GSK189075)

纯度：≥98%

货号：R412671

Cas号：442201-24-3

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Information

Remogliflozin etabonate (GSK189075) is an orally active, selective and low-affinity inhibitor ofsodium glucose cotransporter (SGLT2)with Ki of 1950 nM, 2140 nM, 43100 nM, 8570 nM for hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectively. Remogliflozin etabonate exhibits antidiabetic efficacy in rodent models.

Targets

hSGLT2 (Cell-free assay); rSGLT2 (Cell-free assay); rSGLT1 (Cell-free assay); hSGLT1 (Cell-free assay) 1950 nM(Ki); 2140 nM(Ki); 8570 nM(Ki); 43100 nM(Ki)

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