基本描述
产品名称：Recombinant Human Gremlin 1 Protein
规格或纯度：无载体,生物活性,ActiBioPure™,无叠氮钠,His标签,≥98%(SDS-PAGE)
生物活性：Gremlin 1 is an inhibitor in the TGF-beta signaling pathway. The protein expression is found in many cancers and is thought to play important roles in uterine cervix, lung, ovary, kidney, breast, colon, pancreas, and sarcoma carcinomas. GREM1 and other BMP antagonists are important in the survival of cancer stroma survival and proliferation in some cancers. Measured by its binding ability in a functional ELISA. Immobilized Human BMP-7 at 2 μg/mL can bind Recombinant Human Gremlin 1 Protein (rp146650) with the EC50 of 0.10 μg/mL.
纯度：＞98%(SDS-PAGE)
氨基酸：26-184 aa
N-末端序列：K
无载体：Yes
无动物源：No
Accession #：O60565
预测分子量：24.9 KDa
SDS-PAGE：23.2 kDa, under reducing conditions; 23.2 kDa, under non-reducing conditions.
级别：无载体, 生物活性, ActiBioPure™, 无叠氮钠, His标签
产品规格参数
储存缓冲液：Lyophilized from sterile 10mM PBS, pH 7.4，containing 0.01% SKL, 5% Trehalose .
复溶：Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存温度：-20°C储存,避免反复冻融
运输条件：超低温运输
稳定性与储存：在 2-8℃ 下保存一个月。分装后在 -80℃ 下保存 12 个月。
功能和特点
Accession #：O60565
生物活性：Gremlin 1 is an inhibitor in the TGF-beta signaling pathway. The protein expression is found in many cancers and is thought to play important roles in uterine cervix, lung, ovary, kidney, breast, colon, pancreas, and sarcoma carcinomas. GREM1 and other BMP antagonists are important in the survival of cancer stroma survival and proliferation in some cancers. Measured by its binding ability in a functional ELISA. Immobilized Human BMP-7 at 2 μg/mL can bind Recombinant Human Gremlin 1 Protein (rp146650) with the EC50 of 0.10 μg/mL.
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Protein Bioactivity: Recombinant Human Gremlin 1 Protein (rp146650)
Recombinant Human Gremlin 1 Protein (rp146650) - Protein Bioactivity
Gremlin 1 is an inhibitor in the TGF-beta signaling pathway. The protein expression is found in many cancers and is thought to play important roles in uterine cervix, lung, ovary, kidney, breast, colon, pancreas, and sarcoma carcinomas. GREM1 and other BMP antagonists are important in the survival of cancer stroma survival and proliferation in some cancers.
Measured by its binding ability in a functional ELISA. Immobilized Human BMP-7 at 2 μg/mL can bind Recombinant Human Gremlin 1 Protein (rp146650) with the EC50 of 0.10 μg/mL.
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SDS-PAGE: Recombinant Human Gremlin 1 Protein (rp146650)
Recombinant Human Gremlin 1 Protein (rp146650) - SDS-PAGE
3 μg/lane of Recombinant Human Gremlin 1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 23.2 kDa.
查看阿拉丁官网此产品相关对应页面：https://www.aladdin-e.com/zh_cn/rp146650.html
关键字： Gremlin 1蛋白(GREM1)重组蛋白 ; 重组人类 Gremlin 1 蛋白;Cell proliferation-inducing gene 2 protein ; CKTSF1B1gremlin 1, cysteine knot superfamily, homolog
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阿拉丁目前常备库存试剂产品品种超过7万种，SKU总数超过46万，产品线涵盖了化学试剂、生化试剂、药靶配体、蛋白质和抗体等多个领域，是国内少数化学试剂到生物试剂全面发展的国产试剂品牌，产品同步发布在我们国内外电商平台。