基本描述
产品名称:Recombinant Rat GM-CSF Protein
规格或纯度:ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥98%(SDS-PAGE&HPLC)
产品介绍:
GM-CSF是一种造血生长因子,刺激中性粒细胞和巨噬细胞的发育,促进早期红系巨核细胞和嗜酸性祖细胞的增殖和发育。它由内皮细胞、单核细胞、成纤维细胞和t淋巴细胞产生。GM-CSF抑制中性粒细胞迁移,增强成熟端细胞的功能活性。GM-CSF也被报道对非造血细胞有功能性作用,并可诱导人内皮细胞迁移和增殖。此外,它还能刺激多种肿瘤细胞系的增殖,包括成骨肉瘤、癌和腺癌细胞系。据报道,GM-CSF没有跨物种的生物学效应。重组鼠GM-CSF是一个14.5kDa的球状蛋白,由127个氨基酸残基组成。
生物活性:Measured in a cell proliferation assay using murine FDC-P1 cells. The ED50 for this effect is typically <0.02 ng/mL.
纯度:>98% (SDS-PAGE, HPLC)
氨基酸:18-144 aa
蛋白长度:Full length protein
无载体:Yes
无动物源:Yes
Accession #:P48750
预测分子量:14.5 kDa
SDS-PAGE:13.7 kDa, under reducing conditions; 13.7 kDa, under non-reducing conditions.
级别:无动物源, 无载体, 生物活性, ActiBioPure™, 无叠氮钠, 高性能
产品规格参数
储存缓冲液:Lyophilized from a 0.2µm filtered solution in PBS, pH 7.4
复溶:1.This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. 2. Reconstitute in a sterile aqueous buffer to an appropriate concentration. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.
储存温度:-20°C储存,避免反复冻融
运输条件:超低温运输
稳定性与储存:收货后建议分装,储存在 -20°C 温度下,避免冷冻/解冻循环。
功能和特点
Accession #:P48750
生物活性:Measured in a cell proliferation assay using murine FDC-P1 cells. The ED50 for this effect is typically <0.02 ng/mL.
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Protein Bioactivity: Recombinant Rat GM-CSF Protein (rp155067)
Recombinant Rat GM-CSF Protein (rp155067)-Protein Bioactivity
Measured in a cell proliferation assay using FDC-P1 cells. The ED₅₀ for this effect is typically <0.01ng/mL.

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SDS-PAGE: Recombinant Rat GM-CSF Protein (rp155067)
Recombinant Rat GM-CSF Protein (rp155067)-SDS-PAGE
3μg/lane of Recombinant Rat GM-CSF Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a single band at 13.7 kDa.
查看阿拉丁官网此产品相关对应页面:https://www.aladdin-e.com/zh_cn/rp155067.html



关键字: 重组大鼠粒巨噬细胞集落刺激因子 ; 重组大鼠 GM-CSF 蛋白;Colony stimulating factor 2 (granulocyte-macrophage) ; Colony-stimulating factor
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