Human Cadherin-10 / CDH10 Protein, His Tag
分子别名(Synonym)
Cadherin-10,CDH10,T2-cadherin
表达区间及表达系统(Source)
Human Cadherin-10, His Tag (CA0-H52H5) is expressed from human 293 cells (HEK293). It contains AA Gly 55 - Ala 613 (Accession # Q9Y6N8-1).
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 64.2 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.


背景(Background)
钙粘蛋白(Cadherins)是一大类细胞间粘附分子,参与多种细胞类型的细胞间粘附。在神经系统中,钙粘蛋白对发育的所有阶段都至关重要,包括神经管与外胚层的早期分离、神经元和轴突的分离以及突触的形成。这些分子介导使用细胞质结构域中两个高度保守的氨基酸序列设计的钙离子依赖性同型引物。其中一种钙粘蛋白是Cadherin-10。Cadherin-10最初是从人脑中部分克隆的,但其mRNA也被证明存在于小鼠胸腺(称为T2-cadherin)、小鼠睾丸以及小鼠、大鼠和鸡的发育中的大脑和眼睛中。
关键字: Cadherin-10;CDH10蛋白;CDH10重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。