中文名称:C18-PEG2000-苯硼酸,18碳烷基链-聚乙二醇-苯硼酸
英文名称:C18-PEG-PBA
分子量:400 600 1000 2000 3400 5000 10000
性状:根据分子量,呈现粘稠液体或固体粉末。
纯度:>95%
保存条件 :避光,干燥,-20℃保存
运输:低温运输,避免长时间暴露在阳光下和过度的冻融循环。
仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或诊治,非药用,非食用
产品概述:
Phenylboronic acid (PBA) is a tumor targeting molecule, but its nonspecific interaction with normal cells or other components containing cis-diol residues undoubtedly limits its potential application in tumor targeting drug delivery. Herein, we developed fructose-coated mixed micelles via PBA-terminated polyethylene glycol monostearate (PBA-PEG-C18) and Pluronic P123 (PEG20-PPG70-PEG20) to solve this problem, as the stability of borate formed by PBA and fructose was dramatically dependent on pH. The fluorescence spectroscopic results indicated that the borate formed by PBA and fructose decomposed at a decreased pH, and better binding between PBA and sialic acid (SA) was observed at a low pH. These results implied that the fructose groups decorated on the surface of the micelles could be out-competed by SA at a low pH.
结构式:
其他相关产品:
C18-PEG-PBA C18-聚乙二醇-苯硼酸
COOH-PEG-PBA 羧基-聚乙二醇-苯硼酸
NHS-PEG-PBA 活性酯-聚乙二醇-苯硼酸
PCL-PEG-PBA 聚己内酯-聚乙二醇-苯硼酸
PLA-PEG-PBA 聚乳酸-聚乙二醇-苯硼酸
PLGA-PEG-PBA 聚乳酸羟基乙酸共聚物-聚乙二醇-苯硼酸
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