Made in China Factory whole sale clethodim 24% 240g/l EC OD TC

MAMMALIAN TOXICOLOGY 

Reviews FAO/WHO 86 (see part 2 of the Bibliography).  Oral Acute oral LD50 for male rats 1630, female rats 1360, male mice 2570, female mice 2430 mg/kg.  Skin and eye Acute percutaneous LD50 for rabbits >5000 mg/kg. Moderate skin irritant (rabbits). Not a skin sensitiser (guinea pigs).  Inhalation LC50 (4 h) for rats >3.9 mg/l (total aerosol).  NOEL for mice 30, rats 16, dogs 1 mg/kg daily.  ADI (JMPR) 0.01 mg/kg b.w. [1999]; 0.16 mg/kg (Canada); 0.01 mg/kg (USA).  Toxicity class WHO (a.i.) III (company classification); EPA (formulation) III  

ECOTOXICOLOGY 

Birds Oral LD50 for bobwhite quail >2000 mg/kg. Dietary LC50 for mallard ducks >6000 mg/kg.  Fish LC50 (96 h) for rainbow trout 67, bluegill sunfish >120 mg/l.  Daphnia LC50 (48 h) >120 mg/l; NOEC 60 mg/l.  Algae EC50 (5 d) for fresh-water algae 57.8 mg/l.  Bees LD50 (contact) >100 mg/bee.  Worms LC50 for worms 454 mg/kg soil; NOEL 316 mg/kg soil.  

ENVIRONMENTAL FATE 

Animals Metabolised to the sulfoxide and sulfone.  Plants Metabolised to the sulfoxide, sulfone and S-methyl sulfoxide.  Soil/Environment Aerobic DT50 in soil 1-3 d. Kd 0.08-1.6 (5 soil types).