Mouse Glypican 1 / GPC1 Protein, His Tag
分子别名(Synonym)
Glypican 1,GPC1
表达区间及表达系统(Source)
Mouse Glypican 1, His Tag (GP1-M52H7) is expressed from human 293 cells (HEK293). It contains AA Asp 24 - Ser 529 (Accession # Q9QZF2-1).
Predicted N-terminus: Asp 24
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 57.5 kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
Glypican 1已被证明与SLIT2相互作用。这种蛋白质参与了细胞膜中正常朊病毒蛋白向感染性朊病毒形式的错误折叠。细胞表面硫酸乙酰肝素蛋白多糖由膜相关蛋白核心组成,核心被可变数量的硫酸乙酰肝素链取代。glypican相关的整合膜蛋白多糖家族(GRIPS)的成员包含一个通过糖基磷脂酰肌醇连接锚定在细胞质膜上的核心蛋白。这些蛋白质可能在控制细胞分裂和生长调节中发挥作用。
关键字: Glypican 1;Glypican 1蛋白;GPC1重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。