Mouse IRAK4 Protein, His Tag (active enzyme)
分子别名(Synonym)
IMD67, IPD1, IRAK-4, NY-REN-64, REN64
表达区间及表达系统(Source)
Mouse IRAK4 Protein, His Tag (IR4-M5544) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Ala 459 (Accession # Q8R4K2-1).
Predicted N-terminus: His
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 52.9 kDa. The protein migrates as 53-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
制剂(Formulation)
Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.
Contact us for customized product form or formulation.
运输(Shipping)
This product is supplied and shipped with dry ice, please inquire the shipping cost.
存储(Storage)
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -70°C or lower upon receipt;
-70°C for 3 months under sterile conditions.

背景(Background)
该基因编码一种激酶,在Toll样受体(TLR)和T细胞受体(TCR)信号通路中激活NF-κB。这种蛋白质对大多数先天免疫反应至关重要。该基因的突变导致IRAK4缺陷和复发性侵袭性肺炎球菌疾病。已发现该基因存在编码不同异构体的多种转录变体。
关键字: IRAK4;IRAK4蛋白;IRAK4重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。