2-二环己基磷-2',4',6'-三异丙基联苯564483-18-7

2-二环己基磷-2',4',6'-三异丙基联苯是一种由Buchwald集团开发的空气稳定的富电子联芳基单膦配体2，以增强在交叉偶联反应过程中提高钯催化的反应性。 1、用于深入研究芳烃磺酸酯、芳基卤的钯催化胺化和酰胺化反应的配体； 2、用作钯催化 Suzuki 偶联反应的配体，生成文朵灵的 C-15 类似物； 3、用于钯催化 2-卤代苯胺直接环化生成吲哚和色氨酸。区域规则性聚噻吩的合成。

It is a ligand for increased scope of Pd-catalyzed amination and amidation via arene sulfonates, aryl halides. It is a ligand used in a Pd-catalyzed Suzuki coupling leading to C-15 analogs of vindoline and direct annulation of 2-haloanilines to indoles and tryptophans.
Preferred ligand for greener Sonogashira coupling in TPGS-750-M. It may be used as a ligand in the following reactions: • Preparation of functionalized benzylic sulfones via palladium-catalyzed Negishi cross-coupling between alkyl sulfones and aryl halides. • Along with pre-milled palladium(II) acetate as a pre-catalyst for the Stille cross-coupling of aryl chlorides with tributylarylstannanes to form the corresponding biaryl compounds. •Along with platinum chloride to catalyze the hydrosilylation of terminal arylalkynes with silanes to form functionalized β-(E)-vinylsilanes