4-甲基咪唑
中文名称：4-甲基咪唑
英文名称：4-Methylimidazole
CAS 号：822-36-6
分 子 式：C4H6N2
分 子 量：82.10
结 构 式：
外 观：白色至类白色结晶性粉末
熔 点：54~56℃
密 度：1.02-1.06g/ml
含 量：≥99.5%
用 途：用作环氧树脂的固化剂、药品西咪替丁的主要原料，还可用于合成抗菌剂等。
包 装：25公斤/纸板桶。
运输贮存：本品贮存运输时应轻装轻御，防止破损受潮，严禁与有毒品混存。
检测方法：将含有焦糖色素的样品经固相萃取柱（XTR>500 mg）固相萃取，样品过柱后，用有机溶剂洗脱，洗脱液浓缩后，用微量点样器直接在层析材料聚酰胺薄膜上点样，在装有相应配比的展开剂中上行展开，碘蒸汽显色后肉眼直接观察，如果在比移值0.5~0.7之间同时观察到比移值与标样相同的棕色斑点，则认为该被测物中含有4-甲基咪唑。
该方法可以实现快速定性检测样品是天然酿造还是由人工配制，特别适合对酱油、醋、可乐等含有焦糖色素的样品进行检测。展开后的薄层板可长期保存以备复查，可应用薄层扫描仪进行测定。
制备工艺：1、由丙酮醛、乙醛和氨反应而得。
2、以亚硫酸铵为原料生产焦糖色素的过程中产生。
Product Name:4-Methylimidazole
Another Name:1H-Imidazole, 4-methyl-;1H-Imidazole,4-methyl
CAS No.:822-36-6
EINECS NO.:212-497-3
Molecular Formula:C4H6N2
Molecular weight:82.10
Appearance:Slightly yellow chunks
Purity:≥99.5%
Usage:Imidazole is a heterocyclic compound of five-membered diunsaturated ring structure composed of three carbon atoms and two nitrogen atoms at nonadjacent positions. The simplest member of the imidazole family is imidazole itself, colorless to pale yellow crystalline solid with a weak aminelike odor; soluble in water and alcohol, melts at 89 C, boils at 256 C. Imidazoles are poorly soluble in water generally, but are dissolved in organic solvents, such as chloroform, propylene glycol, and polyethoxylated castor oil. Imidazole ring is found in histidine (an essential amino acid) and histamine, the decarboxylated compound from histamine. Some imidazole compounds inhibit the biosynthesis of ergosterol, required in cell membrane in fungal. They have antibacterial, antifungal, antiprotozoal, and anthelmintic activity. Several distinct phenylimidazoles are therapeutically useful antifungal agents against either superficial or systemic infections. Thiabendazoles which have anthelmintic and antifungal properties are imidazole class compounds. Benzimidazole is a dicyclic compound having midazole ring fused to benzene. Benzimidazole structure is a part of the nucleotide portion of vitamin B12 and the nucleus in some drugs such as proton pump inhibitors and anthelmintic agents. Imidazole has two nitrogen atoms. The one is slightly acidic, while the other is basic. Imidazole and its derivatives are widely used as intermediates in synthesis of organic target compounds including pharmaceuticals, agrochemicals, dyes, photographic chemicals, corrosion inhibitors, epoxy curing agents, adhesives and plastic modifiers.
Packing:25kg/drum
关键字： 咪唑;
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