泼尼松龙

 

泼尼松龙，本品极易由消化道吸收，其本身以活性形式存在，无需经肝脏转化即发挥其生物效应。口服后约l一2小时血药浓度达峰值，T1/2为2～3小时。肌注时，本品磷酸钠盐极易吸收，而其醋酸酯混悬液则吸收缓慢。在血中本品大部分与血浆蛋白结合（但结合率低于氢化可的松），游离的和结合型代谢物自尿中排出，部分以原形排出，小部分可经乳汁排出。

英文名称:prednisolone

中文别名:氢化泼尼松;强的松龙;去氢氢化可的松

英文别名:11-beta,17-alpha; 11,17,21-trihydroxypregna-1,4-diene-3,20-dione; (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate

CAS:50-24-8      EINECS:200-021-7

分子式:C21H28O5     分子量:360.44

药品类别：肾上腺皮质激素类药

性状:常用其醋酸酯，为白色或几乎白色结晶性粉末；无臭，味苦。在乙醇或氯仿中微溶，在水中几乎不溶。与泼尼松同。其疗效与泼尼松相当，其抗炎作用较强、水盐代谢作用很弱。口服可从胃肠道吸收，tl/2约200分钟。由于其盐皮质激素活性很弱，故不适用于原发性肾上腺皮质功能不全症。肾上腺皮质激素类药。主要用于过敏性与炎症性疾病。由于该品潴钠作用较弱，故一般不用作肾上腺皮质功能减退的替代治疗。

 

Shandong Taihua Bio &Tech Co.,Ltd. is a leading manufacturer of steroid raw materials with advanced technics. Established in 2004,and it Locates at the foot of Taishan Mountain. We are a main manufacturer and supplier in hormone raw material field,Our Products are series of intermediates as well as APIs of prednisolone,betamethasone,budesonide,halcinonide for more than 20 products. The API workshop equipped with auto-equipments for producing high-purity raw materials with an annual capacity of 100 Tons. All the staff are professional and skilled. And all the operations strictly conform to th