| 名称 | 1,2,3,6-Tetragalloylglucose |
| 描述 | 1,2,3,6-Tetragalloylglucose (TeGG) has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransferase 1 A1 (UGT1A1, Ki = 1.68 μM). |
| 体外活性 | 两种酚类化合物1,2,6-三没食子酰基葡萄糖（1）和1,2,3,6-Tetragalloylglucose （2），从胡桃属植物（Juglans mandshurica）的树皮中分离出来，并对其抗氧化活性进行了评价。研究结果表明，化合物1和1,2,3,6-Tetragalloylglucose 在清除1,1'-二苯基-1-磺酰基肼（DPPH）、2,2'-氮杂双（3-乙基苯并噻唑啉-6-磺酸）酸（ABTS(*+)）和超氧阴离子（O(2)(*-)）方面表现出强大的活性，并且对脂质过氧化和低密度脂蛋白（LDL）氧化也有显著的抑制效果[1]。 |
| 存储条件 | keep away from direct sunlight,store at low temperature,The compound is unstable in solution. Please use soon,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (4.18 mM), Sonication is recommended.
DMSO : 91 mg/mL (115.4 mM), Sonication is recommended.
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| 关键字 | UGT1A1 | LDL | Inhibitor | inhibit | 1,2,3,6-Tetra-O-galloyl-beta-D-glucose | 1,2,3,6-Tetra-O-galloyl-b-D-glucose | 1,2,3,6-Tetragalloylglucose | 1,2,3,6Tetragalloylglucose | 1,2,3,6 Tetragalloylglucose |
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