TrkC产品信息
英文名称:Neurotrophic tyrosine kinase receptor type 3
中文名称:生长因子受体NT-3
靶点别称:TrkC,NTRK3
物种:Human
标签:Tag Free/Fc Tag
属性:Protein/Cell
标记:Unconjugated
表达区间及表达系统(Source)
Human TrkC Protein, Fc Tag (TRC-H5256) is expressed from human 293 cells (HEK293). It contains AA Cys 32 - Thr 429 (Accession # Q16288-1).
Predicted N-terminus: Cys 32
蛋白结构(Molecular Characterization)

This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 71.2 kDa. The protein migrates as 95-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
原肌球蛋白受体激酶C(TrkC),也称为NT-3生长因子受体、神经营养酪氨酸激酶受体3型或TrkC酪氨酸激酶,是一种在人类中由NTRK3基因编码的蛋白质。它属于原肌球蛋白相关激酶(Trk)受体酪氨酸激酶家族(TrkA、TrkB和TrkC)。
TrkC是神经营养因子NT-3(神经营养因子-3)的高亲和力催化受体。因此,TrkC介导了这种神经营养因子的多种作用,包括神经元分化和存活。
关键字: TrkC;TrkC蛋白;NTRK3蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。