Human CCR9 Full Length Protein, Flag,His Tag (Detergent)
分子别名（Synonym）
C-C motif chemokine receptor 9,GPR28,CDw199,GPR9
表达区间及表达系统（Source）
Human CCR9 Full Length Protein, Flag,His Tag (CC9-H52D3) is expressed from human 293 cells (HEK293). It contains AA Thr 2 - Leu 369 (Accession # P51686-1).
Predicted N-terminus: Asp
蛋白结构（Molecular Characterization）
This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus.
The protein has a calculated MW of 44.9 kDa.
内毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
纯度（Purity）
>90% as determined by SDS-PAGE.
制剂（Formulation）
This product is not suitable for cell based experiments due to cytotoxicity of DDM.
DDM and CHS are INDISPENSABLE to keep membrane protein soluble and active, under no circumastance should you remove DDM and CHS.
DDM/CHS buffer (DC-11) is sold separately and not included in protein, and please contact us if you need the buffer.
If glycerol is not compatible to your application, remove glycerol just before immediate experiment, and NEVER store glycerol-free protein solution.
Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5 with glycerol as protectant.
Contact us for customized product form or formulation.
运输（Shipping）
This product is supplied and shipped with dry ice, please inquire the shipping cost.
存储（Storage）
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -70°C or lower upon receipt;
-70°C for 3 months under sterile conditions.
背景（Background）
该基因编码的蛋白质是一种G蛋白偶联受体，具有七个跨膜结构域，属于β趋化因子受体家族。趋化因子及其受体是胸腺细胞在正常和炎症条件下迁移和成熟的关键调节因子。该基因在小肠和结肠的T淋巴细胞中差异表达，其与趋化因子25的相互作用有助于肠上皮内淋巴细胞归巢到小肠。这表明该基因在引导胃肠道不同部位的免疫反应中起着重要作用。该基因及其唯一配体趋化因子25在多种恶性肿瘤中过表达，与肿瘤增殖、凋亡、侵袭、迁移和耐药性密切相关。该基因定位于趋化因子受体基因簇。已发现该基因存在编码不同异构体的多种转录变体。
关键字： CCR9;CCR9蛋白;CCR9重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group（股票代码：301080）是成立于2010年的跨国生物科技公司，是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球，横跨亚洲、北美洲、欧洲，在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家，与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。