CNTF R alpha产品信息
英文名称:Ciliary neurotrophic factor receptor
中文名称:睫状神经营养因子受体
靶点别称:CNTFR,CNTFRa,CNTFR-Alpha
物种:Human
标签:His Tag
属性:Protein
标记:Unconjugated
表达区间及表达系统(Source)
Human CNTF R alpha, His Tag (CNR-H5225) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Pro 346 (Accession # AAH01492).
Predicted N-terminus: Gln 23
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 37.6 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
睫状神经营养因子受体亚基α(CNTFR或CNTFRα)属于I型细胞因子受体家族和3型亚家族。CNTFR包含两个纤维连接蛋白III型结构域和一个Ig样C2型(免疫球蛋白样)结构域。这种受体及其同源配体支持神经元的存活。该受体与白细胞介素-6受体关系最为密切。这种受体通过糖磷脂酰肌醇连接与细胞膜具有不寻常的连接。
关键字: CNTFR;CNTFRa蛋白;CNTFR重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。