ProS1产品信息
英文名称:Prostate-specific antigen
中文名称:前列腺特异性抗原
靶点别称:ProS1
物种:Human
标签:His Tag
属性:Protein
标记:Unconjugated
表达区间及表达系统(Source)
Human ProS1 Protein, His Tag (PR1-H52H3) is expressed from human 293 cells (HEK293). It contains AA Val 284 - Ser 676 (Accession # P07225).
Predicted N-terminus: Val 284
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 45.6 kDa. The protein migrates as 53-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
ProS1是白细胞免疫球蛋白样受体(LIR)家族的成员,该家族存在于染色体区域19q13.4的基因簇中。编码的蛋白质属于LIR受体的B亚家族,其包含两个或四个细胞外免疫球蛋白结构域、一个跨膜结构域和两到四个基于细胞质免疫受体酪氨酸的抑制基序(ITIM)。受体在免疫细胞上表达,与抗原呈递细胞上的MHC I类分子结合,并传递抑制免疫反应刺激的负信号。它被认为可以控制炎症反应和细胞毒性,以帮助集中免疫反应并限制自身反应性。已发现该基因存在编码不同异构体的多种转录变体。
关键字: ProS1;ProS1蛋白;ProS1重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。