Human KIR2DL5 / CD158f Protein, Fc Tag
分子别名(Synonym)
KIR2DL5,CD158f
表达区间及表达系统(Source)
Human KIR2DL5 / CD158f Protein, Fc Tag (KIA-H5255) is expressed from human 293 cells (HEK293). It contains AA His 22 - His 240 (Accession # Q8N109-1).
Predicted N-terminus: His 22
蛋白结构(Molecular Characterization)

This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 50 kDa. The protein migrates as 63-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM Tris,100 mM Glycine,25 mM Arg,150 mM NaCl,pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
杀伤细胞免疫球蛋白样受体2DL5(KIR2DL5)属于免疫球蛋白超家族,是NK细胞的抑制性受体。KIR2DL5由两个同源基因编码,这两个基因显示拷贝数变异和等位基因多态性——KIR2DL5A和KIR2DL5B,其结构域仅变化2个氨基酸,信号肽仅变化1个氨基酸。KIR2DL5和KIR2DL4形成一个亚家族,其细胞质尾部比其他KIR更长,每个都有一个D0和一个D2型Ig样结构域。
关键字: KIR2DL5;KIR2DL5蛋白;KIR2DL5重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。