CCL24产品信息
英文名称:Chemokine (C-C Motif) Ligand 24
中文名称:趋化因子CCL24
靶点别称:CCL24
物种:Human
标签:His Tag
属性:Protein
标记:Unconjugated
表达区间及表达系统(Source)
Human CCL24, His Tag (CC4-H52H1) is expressed from human 293 cells (HEK293). It contains AA Val 27 - Cys 119 (Accession # O00175).
Predicted N-terminus: Val 27
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 12.3 kDa. The protein migrates as 18-21 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
>90% as determined by SEC-HPLC.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.


背景(Background)
C-C基序趋化因子配体24(CCL24),也称为eotaxin2,属于类似MCP-1的CC趋化因子,主要趋化嗜酸性粒细胞。CCL24可以促进嗜酸性粒细胞与内皮细胞的分离,然后与其唯一的配体结合,促进嗜酸性细胞进入组织。CCL24最初在嗜酸性粒细胞中没有发现,但最初是从单核细胞中分离出来的。最近,发现哮喘患者支气管上皮细胞中CCL24的表达增加。CCL24通过CCR3受体(C-C趋化因子受体3型)促进免疫细胞运输和活化以及促纤维化活性。CCL24和CCR3都参与肺部和皮肤炎症和纤维化。
关键字: CCL24;CCL24蛋白;CCL24重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。