Human JAB1 / COPS5 Protein, Fc Tag
分子别名(Synonym)
JAB1,COPS5
表达区间及表达系统(Source)
Human JAB1 Protein, Fc Tag (JA1-H5553) is expressed from Baculovirus-Insect cells. It contains AA Ala 2 - Ser 334 (Accession # Q92905-1).
Predicted N-terminus: Ala 2
蛋白结构(Molecular Characterization)

This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 63.9 kDa. The protein migrates as 33 kDa and 64-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
Jab1,也称为CSN5,是(COP9)信号体复合体(CSN)的一个组成部分,据报道参与细胞增殖、细胞周期进程和肿瘤发生的调节。作为COP9信号体复合体的一个组成部分,Jab1可以相互调节MED1的稳定性和转录活性,可能是介导HER2+肿瘤侵袭性表型的MED1直接靶基因。
关键字: JAB1;JAB1蛋白;JAB1重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。