Human Fetuin A / FETUA Protein, His Tag
分子别名(Synonym)
AHSG,FETUA,Fetuin A
表达区间及表达系统(Source)
Human Fetuin A, His Tag (FEA-H5221) is expressed from human 293 cells (HEK293). It contains AA Ala 19 - Val 367 (Accession # P02765-1).
Predicted N-terminus: Ala 19
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 38.2 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>98% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.


背景(Background)
α-2-HS-糖蛋白(AHSG)也称为α-2-Z-球蛋白、Ba-α-2-糖蛋白、胎球蛋白-A(FETUA),是一种由A和B链两个亚基组成的糖蛋白,属于半胱氨酸蛋白酶抑制剂家族和胎球蛋白类血浆结合蛋白。AHSG/胎球蛋白A在胚胎细胞和成年肝细胞中高度表达,在单核细胞/巨噬细胞中表达程度较低。胎蛋白是白蛋白等载体蛋白。胎球蛋白-A/AHSG与钙和磷酸盐形成可溶性复合物,因此是不溶性磷酸钙的载体。因此,AHSG/胎球蛋白A是一种有效的病理钙化抑制剂。胎球蛋白A/FETUA促进凋亡细胞的吞噬作用,并在骨发育、钙稳态和胰岛素敏感性中发挥作用。胎球蛋白-A缺乏的小鼠表现出软组织的全身钙化。
关键字: Fetuin A;Fetuin A蛋白;Fetuin A重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。