2-((Tributylstannyl)methoxy)cyclopentanamine is used for the direct synthesis of piperazines and morpholines from aldehydes1. It enables a one-step transformation under mild conditions, making it valuable for medicinal chemistry. The reagent is compatible with aromatic, heteroaromatic, and aliphatic aldehydes, allowing the formation of diverse N-heterocycles. It is particularly useful for synthesizing bioactive molecules commonly found in pharmaceuticals. Air- and moisture-stable, it can be stored for weeks without decomposition.
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