Product name:TCL053
CAS:2361162-70-9
Purity:≥98%
Molecular Weight:874.32
Molecular Formula:C53H95NO8
Applications:TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle[1][2].([1]. Kenjo E, et al. Low immunogenicity of LNP allows repeated administrations of CRISPR-Cas9 mRNA into skeletal muscle in mice. Nat Commun. 2021 Dec 8;12(1):7101.
[2]. Cationic lipid. JPWO2019131839A1.)
上海朗旭生物科技有限公司
联系商家时请提及chemicalbook,有助于交易顺利完成!
上海朗旭-蔡