ABLIM1抗体,Rabbit Polyclonal ABLIM1 Antibody
  • ABLIM1抗体,Rabbit Polyclonal ABLIM1 Antibody
  • ABLIM1抗体,Rabbit Polyclonal ABLIM1 Antibody
  • ABLIM1抗体,Rabbit Polyclonal ABLIM1 Antibody

ABLIM1抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-13
QQ交谈 微信洽谈

产品详情

中文名称:ABLIM1抗体英文名称:Rabbit Polyclonal ABLIM1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3713 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ABLIM1
2025-05-13 ABLIM1抗体 Rabbit Polyclonal ABLIM1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3713 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/15-1/50 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesABLIM; LIMAB1; LIMATIN; abLIM-1
WB Predicted band size88 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human ABLIM1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: P07738(ABLIM1 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P07738(ABLIM1 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是关于ABLIM1抗体的3篇参考文献摘要概括:

1. **文献名称**:*ABLIM1 suppresses melanoma progression by regulating invadopodia formation and extracellular matrix degradation*

**作者**:Smith J, et al.

**摘要**:该研究利用ABLIM1抗体进行免疫印迹和免疫荧光分析,发现ABLIM1通过抑制侵袭伪足的形成和基质金属蛋白酶(MMP)活性,抑制黑色素瘤细胞的侵袭和转移。

2. **文献名称**:*ABLIM1 as a novel biomarker for prognosis in gastric cancer: A tissue microarray study*

**作者**:Li Y, et al.

**摘要**:通过免疫组化(ABLIM1抗体)分析胃癌组织样本,发现ABLIM1低表达与患者预后不良显著相关,提示其可能作为抑癌基因参与胃癌进展。

3. **文献名称**:*ABLIM1 interacts with VASP to regulate neuronal growth cone dynamics*

**作者**:Chen R, et al.

**摘要**:研究利用ABLIM1抗体在神经元细胞中验证其与VASP蛋白的相互作用,揭示ABLIM1通过调节细胞骨架重组影响轴突导向和突触可塑性。

(注:以上文献为虚拟示例,实际文献需通过PubMed/Google Scholar等平台以“ABLIM1 antibody”为关键词检索。)

       

背景信息

ABLIM1 (Actin-Binding LIM Protein 1) is a cytoskeletal protein belonging to the LIM domain-containing protein family, characterized by its ability to interact with actin filaments and participate in cell structure organization, motility, and signal transduction. The LIM domain, a zinc-binding motif, facilitates protein-protein interactions, enabling ABLIM1 to serve as an adaptor molecule linking the actin cytoskeleton to signaling pathways. It is expressed in various tissues, including the nervous system, retina, and muscle, where it contributes to cellular polarity, adhesion, and mechanical stability.

Antibodies targeting ABLIM1 are essential tools for investigating its biological roles and regulatory mechanisms. They are widely used in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect ABLIM1 expression levels, subcellular localization, and interactions with binding partners. Research utilizing ABLIM1 antibodies has highlighted its involvement in neuronal development, photoreceptor maintenance, and cancer progression. For instance, studies suggest ABLIM1 may act as a tumor suppressor in certain cancers, while mutations or dysregulation are linked to retinal degenerative diseases. These antibodies also aid in exploring ABLIM1's role in mechanotransduction and its response to cellular stress. Commercial ABLIM1 antibodies are typically validated for specificity across human, mouse, and rat models, supporting translational research in both physiological and pathological contexts.

       
关键字: ABLIM1抗体;ABLIM1;ABLIM1 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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