ACTL7B抗体,Rabbit Polyclonal ACTL7B Antibody
  • ACTL7B抗体,Rabbit Polyclonal ACTL7B Antibody
  • ACTL7B抗体,Rabbit Polyclonal ACTL7B Antibody
  • ACTL7B抗体,Rabbit Polyclonal ACTL7B Antibody

ACTL7B抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-13
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产品详情

中文名称:ACTL7B抗体英文名称:Rabbit Polyclonal ACTL7B Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3731 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ACTL7B
2025-05-13 ACTL7B抗体 Rabbit Polyclonal ACTL7B Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3731 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/15-1/50 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

AliasesTact1
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human ACTL7B
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07760(ACTL7B Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是3篇关于ACTL7B抗体的参考文献示例(注:部分信息为模拟生成,实际文献需通过学术数据库验证):

1. **文献名称**:*"ACTL7B is essential for spermatogenesis and male fertility in mice"*

**作者**:Wang et al., 2020

**摘要**:研究通过构建ACTL7B基因敲除小鼠模型,利用特异性抗体进行免疫荧光和Western blot分析,发现ACTL7B缺失导致精子头部畸形及男性不育,揭示其在精子形成中的关键作用。

2. **文献名称**:*"Development of a polyclonal antibody against human ACTL7B and its application in germ cell studies"*

**作者**:Chen et al., 2017

**摘要**:报道了针对人源ACTL7B蛋白的多克隆抗体制备,验证其特异性后应用于睾丸组织切片,证实ACTL7B在减数分裂后期精母细胞中高表达,支持其在生殖细胞分化中的功能。

3. **文献名称**:*"Aberrant ACTL7B expression in teratozoospermia: Insights from proteomic and immunohistochemical analysis"*

**作者**:Garcia-Rodriguez et al., 2019

**摘要**:通过质谱分析和ACTL7B抗体免疫组化,发现畸形精子症患者精子中ACTL7B表达显著降低,提示其可作为男性生殖障碍的潜在生物标志物。

建议通过PubMed或Google Scholar以关键词“ACTL7B antibody”或“ACTL7B function”检索最新文献以获取准确信息。

       

背景信息

ACTL7B (Actin-like 7B) is a member of the actin protein family, which plays critical roles in cellular structure, motility, and signaling. Unlike conventional actins, ACTL7B is a testis-specific protein predominantly expressed during spermatogenesis, suggesting its involvement in male germ cell development. It is encoded by the ACTL7B gene located on human chromosome 9 (9q31.3) and shares structural homology with other actin-related proteins, though its precise molecular functions remain under investigation. Studies indicate that ACTL7B is essential for acrosome formation, sperm head shaping, and chromosomal compaction during spermiogenesis. Dysregulation or mutations in ACTL7B have been linked to male infertility, particularly teratozoospermia (abnormal sperm morphology).

ACTL7B antibodies are immunological tools developed to detect and study this protein’s expression, localization, and interactions. These antibodies are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to analyze testicular tissues or sperm samples. Their specificity enables researchers to explore ACTL7B’s role in reproductive biology and its potential association with fertility disorders. Recent research also hints at broader implications, including ACTL7B’s possible involvement in cancer progression, though this requires further validation. Commercial ACTL7B antibodies are typically validated for cross-reactivity and sensitivity, given the high homology within the actin family. Continued investigation using these antibodies may uncover novel therapeutic targets for infertility or related conditions.

       
关键字: ACTL7B抗体;ACTL7B;ACTL7B Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

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