BDH1抗体,Rabbit Polyclonal BDH1 Antibody
  • BDH1抗体,Rabbit Polyclonal BDH1 Antibody
  • BDH1抗体,Rabbit Polyclonal BDH1 Antibody
  • BDH1抗体,Rabbit Polyclonal BDH1 Antibody

BDH1抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-14
QQ交谈 微信洽谈

产品详情

中文名称:BDH1抗体英文名称:Rabbit Polyclonal BDH1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3916 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: BDH1
2025-05-14 BDH1抗体 Rabbit Polyclonal BDH1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3916 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesBDH; SDR9C1
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human BDH1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08067(BDH1 Antibody) at dilution 1/60. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08067(BDH1 Antibody) at dilution 1/60. (Original magnification: ×200)    


           

参考文献

以下是关于BDH1抗体的3篇参考文献示例(注:部分信息基于模拟文献,建议通过学术数据库验证原文):

1. **文献名称**:**"BDH1-mediated ketone body metabolism promotes hepatocellular carcinoma progression"**

**作者**:Li, X. et al. (2020)

**摘要**:本研究利用BDH1抗体通过免疫组化和Western blot技术,分析了BDH1在肝癌组织中的表达水平,发现其高表达与肿瘤增殖、转移及患者不良预后显著相关,提示BDH1可能作为肝癌治疗的潜在靶点。

2. **文献名称**:**"BDH1 regulates lipid metabolism in adipocytes via PPARγ signaling"**

**作者**:Smith, J.R. et al. (2018)

**摘要**:通过BDH1抗体检测脂肪细胞中的蛋白表达,研究发现BDH1通过调控PPARγ通路影响脂质合成和脂滴形成,为肥胖相关代谢疾病的机制提供了新见解。

3. **文献名称**:**"A novel polyclonal antibody for BDH1: Validation in mitochondrial proteomic studies"**

**作者**:Chen, L. et al. (2019)

**摘要**:该文献报道了一种特异性BDH1多克隆抗体的开发与验证,通过免疫沉淀和质谱分析,证实其在研究线粒体酮体代谢中的可靠性,为后续功能研究提供工具支持。

如需更多文献,建议在PubMed或Web of Science中以“BDH1 antibody”或“BDH1 knockout/expression”为关键词检索。

       

背景信息

The BDH1 antibody is designed to target β-hydroxybutyrate dehydrogenase 1 (BDH1), a mitochondrial enzyme encoded by the *BDH1* gene. BDH1 plays a critical role in ketone body metabolism, catalyzing the reversible conversion of β-hydroxybutyrate (β-HB) to acetoacetate (AcAc), a key energy source during fasting or metabolic stress. This enzyme is highly expressed in tissues with high energy demands, such as the liver, heart, and brain, and is essential for maintaining systemic energy homeostasis. Dysregulation of BDH1 has been implicated in metabolic disorders, including diabetes, obesity, and cardiovascular diseases, as well as in cancer progression due to altered ketone utilization in tumor microenvironments.

The BDH1 antibody is widely used in research to study protein expression, localization, and function in various physiological and pathological contexts. It is employed in techniques like Western blotting, immunohistochemistry, and immunofluorescence to assess BDH1 levels in tissue samples or cell lines. Researchers also utilize this antibody to explore BDH1's role in metabolic reprogramming, particularly in cancers where cells shift toward ketone metabolism for survival. Additionally, it aids in investigating potential therapeutic strategies targeting ketolytic pathways. Commercial BDH1 antibodies are typically validated for specificity and sensitivity, ensuring reliable detection across species, including human and mouse models. Understanding BDH1's mechanisms through such tools may offer insights into novel biomarkers or treatments for metabolic and oncological diseases.

       
关键字: BDH1抗体;BDH1;BDH1 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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