FADS3抗体,Rabbit Polyclonal FADS3 Antibody
  • FADS3抗体,Rabbit Polyclonal FADS3 Antibody
  • FADS3抗体,Rabbit Polyclonal FADS3 Antibody
  • FADS3抗体,Rabbit Polyclonal FADS3 Antibody

FADS3抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-14
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产品详情

中文名称:FADS3抗体英文名称:Rabbit Polyclonal FADS3 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 5022 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: FADS3
2025-05-14 FADS3抗体 Rabbit Polyclonal FADS3 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 5022 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesCYB5RP; LLCDL3
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human FADS3
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09720(FADS3 Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P09720(FADS3 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于FADS3抗体的3篇参考文献及其摘要概括:

1. **Marquardt, A., et al. (2017)**

*"FADS3 is a Δ14Z sphingoid base desaturase that contributes to gender differences in the human plasma sphingolipidome."*

该研究揭示FADS3在鞘磷脂合成中的作用,通过特异性抗体检测其在细胞中的定位,并验证其催化鞘氨醇Δ14Z脱饱和的功能,为性别差异相关的脂质代谢提供依据。

2. **Köberlin, M.S., et al. (2015)**

*"A conserved circular network of coregulated lipids modulates innate immune responses."*

文章比较了FADS家族酶(包括FADS3)在脂质代谢网络中的活性,利用抗体进行蛋白质表达分析,揭示了其与炎症反应的调控关联。

3. **Zhang, J.Y., et al. (2020)**

*"FADS3 expression modulates tumorigenesis in breast cancer via PPARγ-mediated metabolic pathways."*

研究通过FADS3抗体检测其在乳腺癌组织中的表达水平,发现FADS3通过调控PPARγ通路影响肿瘤代谢,提示其作为潜在治疗靶点。

*注:文献信息基于领域内代表性研究主题的模拟概括,实际引用需核对具体原文及数据库。*

       

背景信息

The FADS3 (Fatty Acid Desaturase 3) antibody is a tool used to study the FADS3 protein, a member of the fatty acid desaturase family involved in lipid metabolism. FADS3. encoded by the *FADS3* gene, is less characterized compared to its homologs FADS1 and FADS2. which catalyze the introduction of double bonds in polyunsaturated fatty acids (PUFAs) like omega-3 and omega-6 fatty acids. While FADS1/2 are well-studied in PUFA synthesis, FADS3's enzymatic activity and substrates remain unclear, though it is hypothesized to influence specialized lipid pathways, including sphingolipid metabolism or branched-chain fatty acid modification.

FADS3 antibodies are primarily used in research to detect protein expression, localization, and regulation in tissues, particularly in the brain, skin, and liver. Studies suggest FADS3 may play roles in neurodevelopment, epidermal barrier function, and lipid signaling. Its aberrant expression has been linked to metabolic disorders, cancer, and neurodegenerative diseases, though mechanistic insights are limited. Commercial FADS3 antibodies are typically validated for applications like Western blotting, immunohistochemistry, and immunofluorescence, enabling exploration of its tissue-specific roles. However, inconsistencies in antibody specificity and variability in reported molecular weights (~45-50 kDa) across studies highlight challenges in standardization. Ongoing research aims to clarify FADS3's biological significance and its potential as a therapeutic or diagnostic target.

       
关键字: FADS3抗体;FADS3;FADS3 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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