ENTPD1抗体,Rabbit Polyclonal ENTPD1 Antibody
  • ENTPD1抗体,Rabbit Polyclonal ENTPD1 Antibody
  • ENTPD1抗体,Rabbit Polyclonal ENTPD1 Antibody
  • ENTPD1抗体,Rabbit Polyclonal ENTPD1 Antibody

ENTPD1抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-15
QQ交谈 微信洽谈

产品详情

中文名称:ENTPD1抗体英文名称:Rabbit Polyclonal ENTPD1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6633 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ENTPD1
2025-05-15 ENTPD1抗体 Rabbit Polyclonal ENTPD1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6633 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/10-1/50 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

AliasesCD39; SPG64; ATPDase; NTPDase-1
WB Predicted band size58 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenSynthetic peptide of human ENTPD1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: P12402(ENTPD1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P12402(ENTPD1 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是关于ENTPD1抗体的3篇参考文献示例(文献信息为虚构,仅供格式参考):

---

1. **"Anti-CD39 Antibody Therapy Potentiates T Cell-Mediated Cancer Immunotherapy"**

*Authors: Smith A, Patel R*

摘要:研究开发了一种高特异性抗ENTPD1(CD39)单克隆抗体,可阻断肿瘤微环境中ATP水解及腺苷累积,显著增强T细胞抗肿瘤活性并抑制肿瘤生长。

2. **"CD39 Expression in Tumor-Infiltrating Lymphocytes: Validation of a Novel Antibody for Flow Cytometry"**

*Authors: Lee JY, Kim H, et al.*

摘要:报道了一种新型ENTPD1抗体的开发与验证,通过流式细胞术检测肿瘤浸润淋巴细胞中CD39表达,揭示了其与患者预后的相关性。

3. **"Targeting CD39 with Neutralizing Antibodies Reverses Immunosuppression in Chronic Viral Infection"**

*Authors: Zhang T, Müller C*

摘要:利用抗ENTPD1抗体阻断CD39的酶活性,减少腺苷介导的免疫抑制,在慢性病毒感染模型中恢复T细胞功能并降低病毒载量。

---

*注:以上文献为示例,实际研究中请通过PubMed或Google Scholar检索真实发表的论文。*

       

背景信息

ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1), also known as CD39. is a cell surface enzyme encoded by the *ENTPD1* gene. As a member of the ectonucleoside triphosphate diphosphohydrolase family, it plays a critical role in purinergic signaling by hydrolyzing extracellular ATP and ADP into AMP, which is subsequently converted to adenosine by CD73 (ecto-5'-nucleotidase). This enzymatic activity regulates immune responses by modulating extracellular nucleotide levels, thereby influencing purinergic receptor signaling pathways. CD39 is highly expressed on immune cells, including regulatory T cells (Tregs), dendritic cells, and tumor-infiltrating lymphocytes, as well as endothelial cells.

ENTPD1 antibodies are essential tools for studying the protein's expression, function, and therapeutic potential. They are widely used in research to investigate CD39's role in immune tolerance, inflammation, and cancer. In the tumor microenvironment, CD39 contributes to immunosuppression by generating adenosine, which dampens effector T cell activity and promotes tumor immune evasion. Consequently, CD39 is considered a promising target for cancer immunotherapy, with blocking antibodies being explored to enhance antitumor immunity. Additionally, CD39 antibodies aid in understanding its involvement in autoimmune diseases, cardiovascular disorders, and thrombotic conditions linked to dysregulated purinergic signaling. These antibodies are validated for applications such as flow cytometry, immunohistochemistry, and functional assays, supporting both basic research and drug development efforts.

       
关键字: ENTPD1抗体;ENTPD1;ENTPD1 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

店内推荐

ENTPD1抗体相关厂家报价

产品名称 价格   公司名称 报价日期
¥1180
VIP1年
上海抚生实业有限公司
2026-01-30
¥1180
VIP1年
上海博湖生物科技有限公司
2026-01-30
¥1180
VIP1年
上海西格生物科技有限公司
2026-01-30
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.