维百奥生物库存现货，特价销售Recombinant Human IL-2 (carrier-free)！
| 产品信息
品名：Recombinant Human IL-2 (carrier-free)
别名：T-cell growth factor (TCGF), Eosinophil differentiation factor (EDF), Killer cell helper factor (KHF), Macrophage-activating factor for cytotoxicity I (MAF-C I), Thymocyte differentiation factor (TDF)
品牌：Biolegend
货号：589104
规格：25 µg
| 产品描述
IL-2 was discovered through its function as a T cell growth factor (TCGF), and plays a pivotal role in immune responses against pathogenic infection. Recognition and binding of the foreign Ags by the TCRs stimulate both the secretion of IL-2 and the expression of IL-2Rs on the T cell surface. Subsequently, the IL-2/IL-2R interaction activates the intracellular Ras/Raf/MAPK, JAK/STAT, and PI3K/AKT signal pathways, and ultimately stimulates the growth, differentiation, and survival of the Ag-selected cytotoxic T cells. Human IL-2 acts on murine and human T cells, and its receptors are shared by others cytokines. IL-2Rα is an IL-2–specific receptor, IL-2Rβ is shared with IL-15 and the γ chain that is a common receptor shared by many cytokines including IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21.
| 产品细节
1）Source
Human IL-2, amino acids Ala21-Thr153 (Accession # NM_000586), was expressed in insect cells.
2）Molecular Mass
The 133 amino acid recombinant protein (Ala21-Thr153) has a predicted molecular mass of 15418 Da. The DTT-reduced and the non-reduced protein migrate at approximately 15 kD by SDS-PAGE. The N-terminal amino acid is Ala.
3）Purity
Purity is >95%, as determined by Coomassie stained SDS-PAGE.
4）Formulation
The protein was 0.22 µm filtered protein solution is in 0.1% TFA, 30% acetonitrile.
5）Storage & Handling：
Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to six months, or at -70°C or colder until the expiration date. For maximum results, quick spin vial prior to opening. The protein can be aliquoted and stored at -20°C or colder. Stock solutions can also be prepared at 50 - 100 µg/mL in appropriate sterile buffer, carrier protein such as 0.2 - 1% BSA or HSA can be added when preparing the stock solution. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
关键字： Biolegend;T-cell growth factor;IL-2;589104;
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