Product Name：GB-6
CAS No.：2413262-74-3
Synonyms：靶向胃泌素释放肽受体多肽
Catalog No.：220P108
Brand：Typeptide Biotech（肽研生物）
Description：GB-6是一种短线性肽，靶向胃泌素释放肽受体(GRPR)多肽，是由6个氨基酸组成的多肽。GRPR 在胰腺癌中过度表达，基于 GB-6 的肿瘤选择性和肿瘤特异积累特性，近红外 (NIR) 荧光染料或放射性核素锝-99m (99mTc) 标记的 GB-6 可用做高对比度成像探针。GB-6 具有优异体内稳定性，在 SW199 0皮下异种移植模型中，肿瘤与胰腺和肠道荧光信号比分别为 5.2 和 6.3。GB-6 能快速靶向肿瘤，精确描绘肿瘤边界，具有广阔应用前景。
GB-6 is a short peptide that targets the gastrin releasing peptide receptor (GRPR) polypeptide, consisting of 6 amino acids. GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor specific accumulation characteristics of GB-6, GB-6 labeled with near-infrared (NIR) fluorescent dye or radionuclide technetium-99m (99mTc) can be used as a high contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in the SW1990 subcutaneous xenograft model. GB-6 can quickly target tumors, accurately depict tumor boundaries, and has broad application prospects.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Q-{Htp}-{β-Ala}-{Nva}-GH-NH2 |
Sequence(3-letter code) | H-Gln-{Htp}-{β-Ala}-{Nva}-Gly-His-NH2 |
Peptide Structure | 
|
Molecular Formula | C32H45N11O8 |
Molecular Weight | 711.77 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： GB-6;靶向胃泌素释放肽受体多肽;2413262-74-3;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。