Product Name:Dulaglutide
CAS No.:923950-08-7
Synonyms:Dulaglutide - solution in PBS;杜拉鲁肽
Catalog No.:Typeptide Biotech(肽研生物)
Brand:HongTide(上海鸿肽生物)
Description:Dulaglutide是新型长效GLP-1R激动剂多肽,序列中包含31个氨基酸,由两个具有DPP-4 抑制作用的GLP-1类似物和人免疫球蛋白重链IgG4-Fc 片段融合得到,在临床表现中其活性与内源性GLP-1相似,半衰期为5天,能有效延缓肾脏的清除作用。FDA于2014 年9 月批准杜拉鲁肽皮下注射液上市。欧盟委员会于2014年12月批准杜拉鲁肽皮下注射液在欧洲上市。
Dulaglutide is a novel long-acting GLP-1R agonist peptide with a sequence containing 31 amino acids. It is obtained by fusion of two GLP-1 analogues with DPP-4 inhibition and human immunoglobulin heavy chain IgG4-Fc fragments. In clinical manifestations, its activity is similar to endogenous GLP-1, with a half-life of 5 days, and can effectively delay renal clearance. The FDA approved the marketing of Dulaglutide subcutaneous injection in September 2014. The European Commission approved the marketing of Dulaglutide subcutaneous injection in Europe in December 2014.
Purity (HPLC) ≥95.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HGEGTFTSDVSSYLEEQAAKEFIAWLVKGGG |
Sequence(3-letter code) | H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Gly-Gly-OH |
Peptide Structure | 
|
Molecular Formula | C149H221N37O49 |
Molecular Weight | 3314.62 |
订购联系方式:
南京肽研生物生物科技有限公司
手机号:19961912513(微信同号)
QQ: 2178255659
邮箱:sales@typeptide.com
联系人:顾经理
申明:本产品仅供科研使用。
关键字: 923950-08-7;Dulaglutide;杜拉鲁肽;多肽;多肽工厂;
肽研生物坐落于国家级新区南京江北新区新材料产业园,是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神,持续投入研发,不断创新,致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。