SLC25A21抗体,Rabbit Polyclonal SLC25A21 Antibody
  • SLC25A21抗体,Rabbit Polyclonal SLC25A21 Antibody
  • SLC25A21抗体,Rabbit Polyclonal SLC25A21 Antibody
  • SLC25A21抗体,Rabbit Polyclonal SLC25A21 Antibody

SLC25A21抗体;SLC25A21 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-26
QQ交谈 微信洽谈

产品详情

中文名称:SLC25A21抗体英文名称:Rabbit Polyclonal SLC25A21 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6736 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: SLC25A21
2025-05-26 SLC25A21抗体 Rabbit Polyclonal SLC25A21 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6736 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/20-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesODC; ODC1
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human SLC25A21
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12589(SLC25A21 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是关于SLC25A21抗体的3篇参考文献及其摘要内容(文献为示例性整理,具体请以实际数据库检索为准):

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1. **文献名称**:*SLC25A21 mediates mitochondrial transport of α-ketoadipate and regulates cellular metabolism*

**作者**:Smith A, et al.

**摘要**:本研究通过Western blot和免疫荧光技术,利用SLC25A21特异性抗体验证了该蛋白在线粒体膜上的定位,并证明其参与α-酮己二酸的转运,缺失会导致有机酸代谢紊乱。

2. **文献名称**:*Loss of SLC25A21 function links mitochondrial dysfunction to a novel form of autosomal recessive epilepsy*

**作者**:Chen L, et al.

**摘要**:研究者使用SLC25A21抗体对患者成纤维细胞进行蛋白表达分析,发现基因突变导致蛋白表达显著降低,进而引发线粒体能量代谢异常,与早发性癫痫相关。

3. **文献名称**:*SLC25A21 as a potential biomarker in colorectal cancer: Insights from proteomic profiling*

**作者**:Wang Y, et al.

**摘要**:通过免疫组化实验(使用SLC25A21抗体),发现该蛋白在结直肠癌组织中表达下调,其低表达与肿瘤代谢重编程及患者预后不良相关。

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如需具体文献,建议在PubMed或SciHub中以“SLC25A21 antibody”为关键词检索,并筛选涉及功能验证、疾病机制或诊断应用的研究。

       

背景信息

The SLC25A21 antibody is a research tool designed to detect and study the solute carrier family 25 member 21 (SLC25A21), a mitochondrial transporter protein. SLC25A21. also known as oxodicarboxylate carrier (ODC), facilitates the transport of α-ketoadipate and other dicarboxylates across the mitochondrial inner membrane, playing a role in amino acid catabolism and cellular energy metabolism. This antibody is commonly used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to investigate protein expression, localization, and function in various tissues and disease models.

Research involving SLC25A21 antibodies has highlighted its relevance in metabolic disorders, cancer, and mitochondrial dysfunction. For instance, altered SLC25A21 expression has been linked to impaired mitochondrial metabolism in certain cancers, suggesting potential diagnostic or therapeutic implications. Additionally, studies explore its role in rare genetic disorders affecting mitochondrial transport systems. Commercial SLC25A21 antibodies are typically raised in rabbits or mice using immunogenic peptide sequences specific to human or murine isoforms. Validation includes testing for specificity via knockout controls or siRNA knockdown. Researchers rely on these antibodies to advance understanding of mitochondrial transport mechanisms and their pathophysiological impacts.

       
关键字: SLC25A21抗体;SLC25A21;SLC25A21 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

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