ZC3H4抗体,Rabbit Polyclonal ZC3H4 Antibody
  • ZC3H4抗体,Rabbit Polyclonal ZC3H4 Antibody
  • ZC3H4抗体,Rabbit Polyclonal ZC3H4 Antibody
  • ZC3H4抗体,Rabbit Polyclonal ZC3H4 Antibody

ZC3H4抗体;ZC3H4 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-27
QQ交谈 微信洽谈

产品详情

中文名称:ZC3H4抗体英文名称:Rabbit Polyclonal ZC3H4 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6879 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ZC3H4
2025-05-27 ZC3H4抗体 Rabbit Polyclonal ZC3H4 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6879 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/20-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesC19orf7
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human ZC3H4
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P12836(ZC3H4 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于ZC3H4抗体的3篇参考文献示例(注:文献信息为模拟虚构,仅供参考):

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1. **文献名称**:*ZC3H4 regulates nuclear RNA surveillance and promotes transcriptional termination via interaction with the exosome complex*

**作者**:Garzia, A., et al.

**摘要**:本研究利用ZC3H4特异性抗体进行免疫沉淀和染色质免疫共沉淀(ChIP),发现ZC3H4通过与核外泌体复合物结合,调控异常RNA的降解,并影响RNA聚合酶II的转录终止过程。

2. **文献名称**:*ZC3H4 is a key mediator of Polycomb-directed gene silencing in stem cells*

**作者**:Brown, J.A., et al.

**摘要**:通过Western blot和免疫荧光实验,作者发现ZC3H4抗体可特异性识别靶蛋白,并揭示ZC3H4通过与Polycomb抑制复合物(PRC2)互作,在胚胎干细胞中维持基因沉默和染色质稳定性。

3. **文献名称**:*Loss of ZC3H4 disrupts chromatin compaction and promotes glioblastoma invasion*

**作者**:Zhang, L., et al.

**摘要**:该研究使用ZC3H4抗体分析胶质母细胞瘤样本,发现ZC3H4缺失导致染色质结构松散,并通过激活侵袭相关基因(如MMP9)促进肿瘤转移。

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**注意**:以上文献为示例,实际研究中请通过PubMed或Web of Science检索真实发表的论文。

       

背景信息

The ZC3H4 antibody is a research tool designed to target the ZC3H4 protein, a zinc finger-containing protein implicated in transcriptional regulation and RNA processing. ZC3H4 (zinc finger CCCH-type containing 4) is part of the human Integrator complex, which plays a role in RNA polymerase II-dependent transcription termination and nascent RNA processing. Studies suggest ZC3H4 contributes to the stability and function of this complex, particularly in mediating the 3' end processing of specific non-coding RNAs, such as snRNAs and enhancer RNAs. Dysregulation of ZC3H4 has been linked to cellular processes like proliferation, differentiation, and apoptosis, with potential implications in cancer and developmental disorders.

Antibodies against ZC3H4 are typically produced in hosts like rabbits or mice using immunogenic peptides or recombinant protein fragments. These antibodies enable detection of ZC3H4 in techniques such as Western blotting, immunoprecipitation, and immunofluorescence, aiding investigations into its molecular interactions and subcellular localization. Commercial ZC3H4 antibodies are often validated for specificity and affinity, though performance may vary between batches or applications. Recent research highlights ZC3H4's role in tumorigenesis and immune responses, making its antibody a valuable reagent for studying gene expression mechanisms and disease pathways. Ongoing work aims to clarify its precise molecular functions and therapeutic potential.

       
关键字: ZC3H4抗体;ZC3H4;ZC3H4 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
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