ZNF35抗体;ZNF35 Antibody—艾普蒂

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     The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12842(ZNF35 Antibody) at dilution 1/40. (Original magnification: ×200)    

  
  

The ZNF35 antibody is a tool used to study the ZNF35 protein, a member of the zinc finger protein family characterized by conserved C2H2-type zinc finger domains. Zinc finger proteins are critical for DNA binding and transcriptional regulation, often functioning as transcription factors in cellular processes like differentiation, proliferation, and apoptosis. ZNF35. encoded by the ZNF35 gene in humans, is thought to play roles in gene expression modulation, though its precise biological functions remain less characterized compared to other zinc finger proteins. Research suggests potential involvement in developmental regulation and cellular stress responses, but further studies are needed to clarify its mechanisms and targets.

Antibodies targeting ZNF35 are primarily used in experimental settings, such as Western blotting, immunohistochemistry, and immunofluorescence, to detect protein expression, localization, and interactions. These reagents aid in exploring ZNF35's tissue-specific expression patterns, subcellular distribution, and potential dysregulation in diseases like cancer or neurological disorders. Commercial ZNF35 antibodies are typically developed in animal hosts (e.g., rabbits or mice) and validated for specificity via knockout controls or peptide blocking assays. Challenges include ensuring cross-reactivity avoidance due to structural similarities among zinc finger proteins. Current literature on ZNF35 remains limited, highlighting the need for deeper investigation into its physiological and pathological roles.