BMERB1抗体;BMERB1 Antibody—艾普蒂

+ +

•  

   

     The image is immunohistochemistry of paraffin-embedded Human brain tissue using P12982(BMERB1 Antibody) at dilution 1/25. (Original magnification: ×200)    

  
  

The BMERB1 antibody is a research tool designed to target the BMERB1 protein, a molecule implicated in various cellular processes, though its precise biological functions remain under investigation. BMERB1 is hypothesized to play roles in cell cycle regulation, DNA repair, or apoptosis, based on structural similarities to proteins in conserved signaling pathways. It has garnered interest in cancer research due to potential associations with tumor progression or suppression, particularly in studies linking its expression patterns to clinical outcomes in certain malignancies.

This antibody is commonly utilized in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect BMERB1 expression levels in tissues or cell lines. Its development often involves immunizing host species (e.g., rabbits or mice) with purified protein fragments or synthetic peptides derived from BMERB1 sequences. Validation typically includes specificity checks via knockout controls or siRNA-mediated silencing.

While BMERB1's exact mechanistic role is unclear, its study contributes to understanding cellular stress responses and oncogenic pathways. Researchers also explore its diagnostic or prognostic potential in diseases like gliomas or breast cancer. However, further functional studies are needed to clarify its interactions and therapeutic relevance. Commercial availability facilitates its use in both basic and translational research contexts.