DHRS4抗体,Rabbit Polyclonal DHRS4 Antibody
  • DHRS4抗体,Rabbit Polyclonal DHRS4 Antibody
  • DHRS4抗体,Rabbit Polyclonal DHRS4 Antibody
  • DHRS4抗体,Rabbit Polyclonal DHRS4 Antibody

DHRS4抗体;DHRS4 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-28
QQ交谈 微信洽谈

产品详情

中文名称:DHRS4抗体英文名称:Rabbit Polyclonal DHRS4 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 7168 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: DHRS4
2025-05-28 DHRS4抗体 Rabbit Polyclonal DHRS4 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 7168 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/20-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesCR; NRDR; PHCR; PSCD; SDR-SRL; SDR25C1; SDR25C2; SCAD-SRL
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human DHRS4
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P13264(DHRS4 Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P13264(DHRS4 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于DHRS4抗体的3篇示例参考文献(内容为模拟概括,仅供参考):

1. **文献名称**: "DHRS4 functions as a tumor suppressor in hepatocellular carcinoma via regulating retinoic acid signaling"

**作者**: Li X, Wang Y, Chen J

**摘要**: 本研究利用DHRS4特异性抗体,通过免疫组化和Western blot技术,发现DHRS4在肝癌组织中表达显著下调。实验表明,DHRS4通过调控视黄酸代谢通路抑制肿瘤细胞增殖,提示其作为肝癌潜在治疗靶点。

2. **文献名称**: "Epigenetic silencing of DHRS4 promotes colorectal cancer progression by activating Wnt/β-catenin pathway"

**作者**: Zhang H, Liu R, Guo M

**摘要**: 文章通过DHRS4抗体检测结直肠癌样本中的蛋白表达水平,结合甲基化分析,揭示DHRS4因启动子高甲基化而表达沉默。功能实验证实其缺失通过激活Wnt通路促进肿瘤侵袭,抗体验证为关键实验手段。

3. **文献名称**: "Characterization of a novel monoclonal antibody against human DHRS4 for metabolic studies"

**作者**: Smith KA, Johnson TL, Brown P

**摘要**: 本研究报道了一种针对人DHRS4蛋白的单克隆抗体的开发与验证。通过免疫沉淀和免疫荧光技术验证抗体特异性,并应用于肝脏和肾脏组织代谢研究,证明DHRS4在脂类代谢中的重要作用。

**提示**:以上为示例文献,实际文献需通过PubMed/Google Scholar等平台以“DHRS4 antibody”或“DHRS4 function”为关键词检索。建议结合研究领域(如癌症、代谢疾病)进一步筛选。

       

背景信息

The DHRS4 (short-chain dehydrogenase/reductase family member 4) antibody is a tool used to detect and study the DHRS4 protein, which belongs to the short-chain dehydrogenase/reductase (SDR) superfamily. DHRS4 is implicated in various metabolic pathways, including steroid hormone biosynthesis, retinoid metabolism, and detoxification processes. The protein functions as an NADPH-dependent reductase, catalyzing the conversion of carbonyl compounds to their corresponding alcohols. It is encoded by the DHRS4 gene located on human chromosome 1 (1p36.22) and is expressed in multiple tissues, such as the liver, kidney, and brain.

DHRS4 has garnered interest due to its evolutionary conservation and the presence of two pseudogenes (DHRS4L1 and DHRS4L2) in its genomic locus, which may influence its regulation. Studies suggest its involvement in cellular redox homeostasis and potential roles in cancer, neurodegenerative diseases, and metabolic disorders. The DHRS4 antibody is commonly used in applications like Western blotting, immunohistochemistry, and immunofluorescence to localize and quantify the protein in biological samples. Researchers also utilize it to explore DHRS4's interactions with substrates or binding partners, its tissue-specific expression patterns, and its regulatory mechanisms under stress or disease conditions. Validation of the antibody typically includes knockout controls or knockdown experiments to confirm specificity. Its development aids in elucidating DHRS4's physiological functions and its relevance to human health.

       
关键字: DHRS4抗体;DHRS4;DHRS4 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
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