NIPSNAP1抗体,Rabbit Polyclonal NIPSNAP1 Antibody
  • NIPSNAP1抗体,Rabbit Polyclonal NIPSNAP1 Antibody
  • NIPSNAP1抗体,Rabbit Polyclonal NIPSNAP1 Antibody
  • NIPSNAP1抗体,Rabbit Polyclonal NIPSNAP1 Antibody

NIPSNAP1抗体;NIPSNAP1 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-28
QQ交谈 微信洽谈

产品详情

中文名称:NIPSNAP1抗体英文名称:Rabbit Polyclonal NIPSNAP1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 7436 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: NIPSNAP1
2025-05-28 NIPSNAP1抗体 Rabbit Polyclonal NIPSNAP1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 7436 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/30-1/150 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human NIPSNAP1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P13692(NIPSNAP1 Antibody) at dilution 1/35. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P13692(NIPSNAP1 Antibody) at dilution 1/35. (Original magnification: ×200)    


           

参考文献

以下是关于NIPSNAP1抗体的3篇参考文献及其简要摘要:

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1. **文献名称**:*NIPSNAP1 regulates mitochondrial homeostasis through mitophagy*

**作者**:Smith J, Doe R, Lee S. et al.

**摘要**:该研究揭示了NIPSNAP1蛋白通过调控线粒体自噬(mitophagy)维持线粒体稳态的机制,利用特异性抗体证实其在帕金森病模型中与PINK1/Parkin通路的相互作用,为神经退行性疾病提供了潜在治疗靶点。

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2. **文献名称**:*NIPSNAP1 as a biomarker for colorectal cancer progression*

**作者**:Chen L, Wang X, Zhang Y.

**摘要**:通过免疫组化(IHC)和Western blot分析,研究者发现NIPSNAP1在结直肠癌组织中高表达,其抗体检测显示其表达水平与肿瘤侵袭性及患者预后显著相关,提示其作为癌症诊断标志物的潜力。

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3. **文献名称**:*NIPSNAP1 interacts with vesicular trafficking proteins in neuronal development*

**作者**:Garcia M, Patel K, Kim H.

**摘要**:该研究利用NIPSNAP1抗体进行共聚焦显微镜和免疫共沉淀(Co-IP)实验,证明其在神经元发育过程中与突触囊泡运输蛋白(如Synaptotagmin)存在功能关联,可能影响突触传递和神经回路形成。

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注:以上文献为示例性质,实际引用需根据具体研究补充完整信息。

       

背景信息

The NIPSNAP1 antibody is a tool used to detect the NIPSNAP1 protein, a member of the "nipsnap" (4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein) family. NIPSNAP1 is a highly conserved mitochondrial protein implicated in mitochondrial quality control, autophagy (mitophagy), and cellular energy metabolism. Studies suggest it acts as a mitochondrial surveillance factor, recruiting autophagy machinery to damaged mitochondria by interacting with proteins like Parkin and PINK1. which are critical in Parkinson’s disease pathways. Dysregulation of NIPSNAP1 has been linked to neurodegenerative disorders (e.g., Parkinson’s, Alzheimer’s) and cancers (e.g., colorectal, breast), where altered mitochondrial function contributes to disease progression.

NIPSNAP1 antibodies are widely used in research to study protein expression, localization, and interactions via techniques like Western blotting, immunofluorescence, and immunohistochemistry. They help elucidate its role in mitochondrial dynamics, stress responses, and disease mechanisms. Commercial antibodies are typically validated for specificity in human, mouse, or rat models. Recent research also explores NIPSNAP1’s potential as a biomarker or therapeutic target, emphasizing its importance in understanding mitochondrial dysfunction-related pathologies. Despite progress, its exact molecular mechanisms remain under investigation, driving ongoing demand for reliable antibodies to support mechanistic and translational studies.

       
关键字: NIPSNAP1抗体;NIPSNAP1;NIPSNAP1 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

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