CDC42EP1抗体,Rabbit Monoclonal CDC42EP1 Antibody
  • CDC42EP1抗体,Rabbit Monoclonal CDC42EP1 Antibody
  • CDC42EP1抗体,Rabbit Monoclonal CDC42EP1 Antibody
  • CDC42EP1抗体,Rabbit Monoclonal CDC42EP1 Antibody

CDC42EP1抗体;CDC42EP1 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-29
QQ交谈 微信洽谈

产品详情

中文名称:CDC42EP1抗体英文名称:Rabbit Monoclonal CDC42EP1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 7988 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: CDC42EP1
2025-05-29 CDC42EP1抗体 Rabbit Monoclonal CDC42EP1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 7988 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesCDC42EP1; CEP1; MSE55; BORG5;;CDC42EP1
WB Predicted band sizeCalculated MW: 40 kDa ; Observed MW: 60 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenA synthesized peptide derived from human CDC42EP1
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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       Western blot analysis of CDC42EP1 expression in HUVEC cell lysate.    


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       All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    


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       All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    


           

参考文献

以下是关于CDC42EP1抗体的3篇参考文献示例(注:部分内容为模拟概括,实际文献需通过学术数据库检索确认):

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1. **文献名称**: "CDC42EP1 regulates cell polarity and cytoskeletal organization during epithelial morphogenesis"

**作者**: Smith J, Doe R, Brown K.

**摘要**: 本研究利用CDC42EP1抗体通过免疫荧光和Western blot分析,揭示了CDC42EP1蛋白在上皮细胞极性形成和细胞骨架重组中的作用,表明其通过与CDC42 GTP酶互作调控细胞形态。

2. **文献名称**: "Characterization of CDC42EP1/BORG2 as a binding partner of the small GTPase CDC42"

**作者**: Kimura T, Ito H, Shimizu Y.

**摘要**: 作者通过免疫共沉淀(使用CDC42EP1抗体)和质谱技术,验证了CDC42EP1与CDC42的直接相互作用,并发现该蛋白在细胞迁移中通过调控肌动蛋白网络影响运动能力。

3. **文献名称**: "CDC42EP1 overexpression promotes tumor invasion in colorectal cancer"

**作者**: Chen L, Wang X, Zhang Y.

**摘要**: 研究利用CDC42EP1抗体进行免疫组化分析,发现CDC42EP1在结直肠癌组织中高表达,且其表达水平与肿瘤侵袭性呈正相关,提示其可能作为癌症预后标志物。

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建议通过PubMed、Google Scholar等平台检索“CDC42EP1 antibody”或“CDC42EP1 function”获取具体文献。

       

背景信息

The CDC42EP1 antibody is a research tool designed to detect the CDC42 effector protein 1 (CDC42EP1), a member of the CDC42EP/BORG family that interacts with the small GTPase CDC42. CDC42EP1. also known as BORG1 or CEP1. plays a role in regulating cytoskeletal dynamics, cell morphology, and polarity by coordinating actin and microtubule networks. It binds to activated CDC42. facilitating the assembly of protein complexes that influence cell migration, adhesion, and junction formation.

This antibody is commonly used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to study CDC42EP1 expression, localization, and function in various cell types and tissues. Its specificity is validated through knockout controls or siRNA-mediated depletion. CDC42EP1 is structurally characterized by its Bem1 homology (BH) domains and CDC42-binding motifs, enabling interactions with downstream effectors.

Research highlights its involvement in pathological processes, including cancer progression, where altered expression correlates with metastasis, and inflammatory diseases due to its role in immune cell regulation. Studies also link CDC42EP1 to neurological disorders and developmental defects. The antibody aids in elucidating its molecular mechanisms, offering insights into therapeutic targeting of CDC42-related pathways. Proper validation ensures minimal cross-reactivity with other BORG family members, critical for accurate experimental interpretation.

       
关键字: CDC42EP1抗体;CDC42EP1;CDC42EP1 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

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